STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKNParkin RBR E3 ubiquitin protein ligase. (462 aa)    
Predicted Functional Partners:
PINK1
PTEN induced kinase 1.
    
 0.997
ENSTBEP00000003983
annotation not available
    
0.990
MFN2
Mitofusin 2.
    
 0.989
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough.
    
 0.988
MFN1
Mitofusin 1.
    
 0.987
RHOT1
Ras homolog family member T1.
    
 0.983
SNCAIP
Synuclein alpha interacting protein.
    
 0.982
SNCA
Synuclein alpha.
    
 0.979
PSMD4
Proteasome 26S subunit, non-ATPase 4.
    
 0.979
ENSTBEP00000007021
annotation not available
    
 0.978
Your Current Organism:
Tupaia belangeri
NCBI taxonomy Id: 37347
Other names: T. belangeri, Tupaia glis belangeri, common tree shrew, northern tree shrew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.