STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHEK2Checkpoint kinase 2. (435 aa)    
Predicted Functional Partners:
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.995
ATR
ATR serine/threonine kinase.
    
 0.995
ENSTBEP00000002149
annotation not available
   
0.994
ATM
ATM serine/threonine kinase.
    
 0.990
ENSTBEP00000010189
annotation not available
    
 0.980
CDC7
Cell division cycle 7.
    
 
 0.973
ENSTBEP00000011274
annotation not available
   
 0.968
ENSTBEP00000003772
annotation not available
   
 
0.963
MCM4
Minichromosome maintenance complex component 4.
   
 
 0.953
PPP2R2B
Protein phosphatase 2 regulatory subunit Bbeta.
    
 
 0.949
Your Current Organism:
Tupaia belangeri
NCBI taxonomy Id: 37347
Other names: T. belangeri, Tupaia glis belangeri, common tree shrew, northern tree shrew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.