STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PBRA_004527SP-RING-type domain-containing protein. (500 aa)    
Predicted Functional Partners:
PBRA_003131
Ubiquitin-like domain-containing protein.
    
 0.999
PBRA_008609
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.993
PBRA_002626
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 
 0.914
PBRA_006309
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.880
PBRA_008025
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.880
PBRA_008507
SP-RING-type domain-containing protein.
    
 
 0.822
PBRA_005418
Uncharacterized protein.
    
 
 0.797
PBRA_001366
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.785
PBRA_009265
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.785
PBRA_001683
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.779
Your Current Organism:
Plasmodiophora brassicae
NCBI taxonomy Id: 37360
Other names: P. brassicae
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