STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PBRA_002558Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (204 aa)    
Predicted Functional Partners:
PBRA_005986
Fip1 domain-containing protein.
   
 0.975
PBRA_001770
Uncharacterized protein.
    
 0.956
PBRA_002009
Uncharacterized protein.
    
 0.956
PBRA_006130
Cleavage and polyadenylation specificity factor subunit 2.
   
 
 0.883
PBRA_004893
WD_REPEATS_REGION domain-containing protein.
     
 0.877
PBRA_002674
CID domain-containing protein.
    
 0.858
PBRA_003344
RRM domain-containing protein.
   
 0.852
PBRA_005628
Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.
   
 0.841
PBRA_004642
TPR_REGION domain-containing protein.
   
 
 0.822
PBRA_005481
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
 0.819
Your Current Organism:
Plasmodiophora brassicae
NCBI taxonomy Id: 37360
Other names: P. brassicae
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