STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (115 aa)    
Predicted Functional Partners:
hypB
Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.895
AQQ60299.1
Hydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.868
AQQ59549.1
Sodium:proton antiporter; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.819
AQQ58915.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.816
AQQ58913.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.799
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 
 0.771
ureA
Urease subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the urease beta subunit family.
     
 0.584
hypC
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.577
hypD
Hydrogenase formation protein HypD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family.
 
  
 0.564
hypE
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.546
Your Current Organism:
Helicobacter bilis
NCBI taxonomy Id: 37372
Other names: ATCC 51630, CCUG 38995 B, CIP 104752, Flexispira rappini species 8, Flexispira taxon 9, H. bilis, Helicobacter sp. ATCC 43879, Helicobacter sp. ATCC 49314, Helicobacter sp. ATCC 49317, Helicobacter sp. ATCC 49320, strain Hb1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.