Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AQQ59515.1Twitching motility protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)    
Predicted Functional Partners:
AQQ60033.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.849
AQQ59516.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.800
AQQ60667.1
Prepilin-type N-terminal cleavage/methylation domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.753
AQQ59828.1
Pilus assembly protein MshL; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.685
AQQ59713.1
General secretion pathway protein GspE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
0.516
AQQ60074.1
Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.511
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.493
dnaN
DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.424
AQQ60075.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.417
AQQ60232.1
Chemotaxis protein CheV; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.417
Your Current Organism:
Helicobacter bilis
NCBI taxonomy Id: 37372
Other names: ATCC 51630, CCUG 38995 B, CIP 104752, Flexispira rappini species 8, Flexispira taxon 9, H. bilis, Helicobacter sp. ATCC 43879, Helicobacter sp. ATCC 49314, Helicobacter sp. ATCC 49317, Helicobacter sp. ATCC 49320, strain Hb1
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.