Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACL68970.1PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; 4Fe-4S binding domain. (491 aa)    
Predicted Functional Partners:
ACL69389.1
PFAM: 4Fe-4S binding domain; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 51 Kd subunit.
  
 
 0.931
ACL68942.1
PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; 4Fe-4S binding domain; 4Fe-4S binding domain.
  
 
 0.929
ACL68968.1
PFAM: Stage II sporulation protein E (SpoIIE).
 
     0.854
ACL68969.1
Hypothetical protein.
 
 
 0.850
ACL68967.1
Putative PAS/PAC sensor protein; PFAM: Putative Fe-S cluster; 4Fe-4S binding domain; 4Fe-4S binding domain; Iron only hydrogenase large subunit, C-terminal domain; TIGRFAM: PAS domain S-box.
 
    
0.783
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.779
ACL68972.1
PFAM: Iron-containing alcohol dehydrogenase; Aldehyde dehydrogenase family; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.708
ACL70827.1
PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S binding domain; 4Fe-4S binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
   
 
 0.667
ACL70678.1
Small GTP-binding protein; PFAM: GTPase of unknown function; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein Era; GTP-binding conserved hypothetical protein; small GTP-binding protein domain.
 
     0.643
ACL68940.1
Serine/threonine specific protein phosphatase; PFAM: Stage II sporulation protein E (SpoIIE).
 
     0.586
Your Current Organism:
Halothermothrix orenii
NCBI taxonomy Id: 373903
Other names: H. orenii H 168, Halothermothrix orenii H 168, Halothermothrix orenii str. H 168, Halothermothrix orenii strain H 168
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.