STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACL69343.1Sporulation sigma factor SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (232 aa)    
Predicted Functional Partners:
ACL69416.1
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.842
ACL69415.1
PFAM: SpoIVB peptidase S55; PDZ domain (Also known as DHR or GLGF); TIGRFAM: stage IV sporulation protein B.
  
   
 0.778
ACL69811.1
TIGRFAM: stage IV sporulation protein A.
  
     0.773
ACL69462.1
PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC.
  
     0.771
ACL69463.1
PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
     0.770
ACL69464.1
PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AE.
  
     0.770
ACL68807.1
PFAM: YabP family; TIGRFAM: sporulation protein YabP.
  
     0.767
ACL70523.1
PFAM: helix-turn-helix, Psq domain; TIGRFAM: sporulation transcriptional regulator SpoIIID.
  
   
 0.763
ACL70864.1
Transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: stage V sporulation protein T; looped-hinge helix DNA binding domain, AbrB family.
  
     0.760
ACL68773.1
PFAM: Bacillus/Clostridium GerA spore germination protein.
  
     0.756
Your Current Organism:
Halothermothrix orenii
NCBI taxonomy Id: 373903
Other names: H. orenii H 168, Halothermothrix orenii H 168, Halothermothrix orenii str. H 168, Halothermothrix orenii strain H 168
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