STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (368 aa)    
Predicted Functional Partners:
ACL70704.1
O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Beta-eliminating lyase; DegT/DnrJ/EryC1/StrS aminotransferase family; Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase; O-succinylhomoserine sulfhydrylase.
 
 0.993
ACL69559.1
PFAM: Homoserine dehydrogenase; ACT domain; Homoserine dehydrogenase, NAD binding domain.
 
 
 0.980
ACL69561.1
PFAM: Amino acid kinase family; ACT domain; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
    
 0.910
ACL69624.1
PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; Belongs to the aspartokinase family.
    
 0.910
ACL70706.1
Homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; B12 binding domain; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase.
  
  
 0.845
ACL69687.1
Threonine dehydratase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form; threonine ammonia-lyase, biosynthetic, long form.
  
 
 0.828
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.828
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.805
ACL70382.1
PFAM: Serine dehydratase alpha chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit.
     
  0.800
ACL70383.1
PFAM: ACT domain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit.
     
  0.800
Your Current Organism:
Halothermothrix orenii
NCBI taxonomy Id: 373903
Other names: H. orenii H 168, Halothermothrix orenii H 168, Halothermothrix orenii str. H 168, Halothermothrix orenii strain H 168
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.