STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACL70827.1PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S binding domain; 4Fe-4S binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric. (1179 aa)    
Predicted Functional Partners:
ACL69286.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 0.999
ACL69287.1
Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family.
  
 0.999
ACL69435.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain; Transketolase, C-terminal domain.
  
0.999
ACL69436.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
 0.999
ACL70816.1
Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
0.999
ACL70817.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain.
 
0.999
ACL70818.1
Pyruvate ferredoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family.
  
 0.998
ACL70819.1
PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family.
  
0.998
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.994
ACL68973.1
Biotin (acetyl-CoA carboxylase) synthetase; PFAM: HI0933-like protein; FAD binding domain; FAD dependent oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit.
  
 
 0.992
Your Current Organism:
Halothermothrix orenii
NCBI taxonomy Id: 373903
Other names: H. orenii H 168, Halothermothrix orenii H 168, Halothermothrix orenii str. H 168, Halothermothrix orenii strain H 168
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.