node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACL70741.1 | ychF | Hore_19940 | Hore_23370 | Threonine aldolase; PFAM: Aminotransferase class-V; Aminotransferase class I and II; Beta-eliminating lyase. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.871 |
ACL71083.1 | ychF | Hore_23380 | Hore_23370 | PFAM: Bacterial protein of unknown function (DUF951). | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.853 |
argS | guaA | Hore_08210 | Hore_02020 | PFAM: tRNA synthetases class I (R); DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; TIGRFAM: arginyl-tRNA synthetase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.987 |
argS | lepA | Hore_08210 | Hore_12840 | PFAM: tRNA synthetases class I (R); DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; TIGRFAM: arginyl-tRNA synthetase. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.618 |
argS | metG-2 | Hore_08210 | Hore_20300 | PFAM: tRNA synthetases class I (R); DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; TIGRFAM: arginyl-tRNA synthetase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.947 |
argS | pheT | Hore_08210 | Hore_05640 | PFAM: tRNA synthetases class I (R); DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; TIGRFAM: arginyl-tRNA synthetase. | phenylalanyl-tRNA synthetase, beta subunit; PFAM: Putative tRNA binding domain; Ferredoxin-fold anticodon binding domain; tRNA synthetase B5 domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.877 |
argS | prfA | Hore_08210 | Hore_17970 | PFAM: tRNA synthetases class I (R); DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; TIGRFAM: arginyl-tRNA synthetase. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.591 |
argS | ychF | Hore_08210 | Hore_23370 | PFAM: tRNA synthetases class I (R); DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; TIGRFAM: arginyl-tRNA synthetase. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.723 |
guaA | argS | Hore_02020 | Hore_08210 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | PFAM: tRNA synthetases class I (R); DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; TIGRFAM: arginyl-tRNA synthetase. | 0.987 |
guaA | lepA | Hore_02020 | Hore_12840 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.665 |
guaA | metG-2 | Hore_02020 | Hore_20300 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.852 |
guaA | pheT | Hore_02020 | Hore_05640 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase, beta subunit; PFAM: Putative tRNA binding domain; Ferredoxin-fold anticodon binding domain; tRNA synthetase B5 domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.936 |
guaA | pth | Hore_02020 | Hore_21210 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.723 |
guaA | topA | Hore_02020 | Hore_07540 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.661 |
guaA | ychF | Hore_02020 | Hore_23370 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.792 |
lepA | argS | Hore_12840 | Hore_08210 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | PFAM: tRNA synthetases class I (R); DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; TIGRFAM: arginyl-tRNA synthetase. | 0.618 |
lepA | guaA | Hore_12840 | Hore_02020 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.665 |
lepA | metG-2 | Hore_12840 | Hore_20300 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.560 |
lepA | pheT | Hore_12840 | Hore_05640 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | phenylalanyl-tRNA synthetase, beta subunit; PFAM: Putative tRNA binding domain; Ferredoxin-fold anticodon binding domain; tRNA synthetase B5 domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.630 |
lepA | prfA | Hore_12840 | Hore_17970 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.793 |