AFY55275.1 protein (Rivularia sp. PCC7116) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AFY55275.1

PFAM: Protein of unknown function (DUF1399). (174 aa)

Predicted Functional Partners:

AFY56146.1

0.733

AFY53008.1

0.712

AFY55276.1

0.710

AFY57627.1

0.689

AFY58145.1

0.605

AFY53113.1

0.561

AFY55274.1

0.448

Your Current Organism:

Rivularia sp. PCC7116

NCBI taxonomy Id: 373994
Other names: Calothrix sp. ATCC 29111, Calothrix sp. PCC 7116, R. sp. PCC 7116, Rivularia sp. LIP, Rivularia sp. PCC 7116

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFY53008.1	AFY55275.1	Riv7116_0405	Riv7116_2776	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	PFAM: Protein of unknown function (DUF1399).	0.712
AFY53113.1	AFY55275.1	Riv7116_0516	Riv7116_2776	PFAM: Acetyltransferase (GNAT) family.	PFAM: Protein of unknown function (DUF1399).	0.561
AFY53113.1	AFY56146.1	Riv7116_0516	Riv7116_3700	PFAM: Acetyltransferase (GNAT) family.	DNA-directed RNA polymerase specialized sigma subunit, sigma24; PFAM: Sigma-70, region 4; Tetratricopeptide repeat; NB-ARC domain.	0.560
AFY55274.1	AFY55275.1	Riv7116_2775	Riv7116_2776	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.	PFAM: Protein of unknown function (DUF1399).	0.448
AFY55275.1	AFY53008.1	Riv7116_2776	Riv7116_0405	PFAM: Protein of unknown function (DUF1399).	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	0.712
AFY55275.1	AFY53113.1	Riv7116_2776	Riv7116_0516	PFAM: Protein of unknown function (DUF1399).	PFAM: Acetyltransferase (GNAT) family.	0.561
AFY55275.1	AFY55274.1	Riv7116_2776	Riv7116_2775	PFAM: Protein of unknown function (DUF1399).	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.	0.448
AFY55275.1	AFY55276.1	Riv7116_2776	Riv7116_2777	PFAM: Protein of unknown function (DUF1399).	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	0.710
AFY55275.1	AFY56146.1	Riv7116_2776	Riv7116_3700	PFAM: Protein of unknown function (DUF1399).	DNA-directed RNA polymerase specialized sigma subunit, sigma24; PFAM: Sigma-70, region 4; Tetratricopeptide repeat; NB-ARC domain.	0.733
AFY55275.1	AFY57627.1	Riv7116_2776	Riv7116_5232	PFAM: Protein of unknown function (DUF1399).	Transcriptional regulator with NB-ARC domain; PFAM: NB-ARC domain.	0.689
AFY55275.1	AFY58145.1	Riv7116_2776	Riv7116_5779	PFAM: Protein of unknown function (DUF1399).	PFAM: BNR/Asp-box repeat.	0.605
AFY55276.1	AFY55275.1	Riv7116_2777	Riv7116_2776	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	PFAM: Protein of unknown function (DUF1399).	0.710
AFY56146.1	AFY53113.1	Riv7116_3700	Riv7116_0516	DNA-directed RNA polymerase specialized sigma subunit, sigma24; PFAM: Sigma-70, region 4; Tetratricopeptide repeat; NB-ARC domain.	PFAM: Acetyltransferase (GNAT) family.	0.560
AFY56146.1	AFY55275.1	Riv7116_3700	Riv7116_2776	DNA-directed RNA polymerase specialized sigma subunit, sigma24; PFAM: Sigma-70, region 4; Tetratricopeptide repeat; NB-ARC domain.	PFAM: Protein of unknown function (DUF1399).	0.733
AFY56146.1	AFY58145.1	Riv7116_3700	Riv7116_5779	DNA-directed RNA polymerase specialized sigma subunit, sigma24; PFAM: Sigma-70, region 4; Tetratricopeptide repeat; NB-ARC domain.	PFAM: BNR/Asp-box repeat.	0.418
AFY57627.1	AFY55275.1	Riv7116_5232	Riv7116_2776	Transcriptional regulator with NB-ARC domain; PFAM: NB-ARC domain.	PFAM: Protein of unknown function (DUF1399).	0.689
AFY58145.1	AFY55275.1	Riv7116_5779	Riv7116_2776	PFAM: BNR/Asp-box repeat.	PFAM: Protein of unknown function (DUF1399).	0.605
AFY58145.1	AFY56146.1	Riv7116_5779	Riv7116_3700	PFAM: BNR/Asp-box repeat.	DNA-directed RNA polymerase specialized sigma subunit, sigma24; PFAM: Sigma-70, region 4; Tetratricopeptide repeat; NB-ARC domain.	0.418

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

27

PPI enrichment p-value:

1.05e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 104

1.5

3.1

6.57e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

10 of 40

1.87

5.09

5.87e-16

GO:0003735

Structural constituent of ribosome

11 of 51

1.81

5.01

2.68e-17

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 57

1.76

4.78

1.76e-17

GO:0044391

Ribosomal subunit

4 of 12

2.0

2.62

2.79e-06

GO:0015934

Large ribosomal subunit

3 of 6

2.17

2.24

4.01e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:34833134

(2021) Genome-Wide Investigation and Analysis of Microsatellites and Compound Microsatellites in Leptolyngbya-like Species, Cyanobacteria.

6 of 15

2.08

4.05

8.68e-10

PMID:32977771

(2020) Role of diversity-generating retroelements for regulatory pathway tuning in cyanobacteria.

2 of 2

2.47

1.47

0.0019

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:151

rRNA-binding

10 of 13

2.36

8.32

1.13e-19

CL:149

rRNA-binding

11 of 21

2.19

7.89

7.79e-21

CL:152

Mixed, incl. Large ribosomal subunit, and K Homology domain, type 2

6 of 7

2.41

5.29

1.63e-11

CL:165

KOW (Kyprides, Ouzounis, Woese) motif., and rRNA-binding

4 of 6

2.3

3.19

4.89e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cgc03010

Ribosome

11 of 53

1.79

5.02

6.52e-18

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

8 of 39

1.79

3.73

3.88e-11

GOCC:0044391

Ribosomal subunit

6 of 19

1.97

3.67

2.96e-09

GOCC:0022626

Cytosolic ribosome

4 of 16

1.87

2.28

1.04e-05

GOCC:0015934

Large ribosomal subunit

3 of 6

2.17

2.13

6.70e-05

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 13

1.84

1.65

0.00036

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

10 of 39

1.88

5.26

1.55e-16

KW-0689

Ribosomal protein

11 of 57

1.76

4.76

2.68e-17

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Fusion

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About