AFY56042.1 protein (Rivularia sp. PCC7116) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

AFY56042.1

Conserved repeat protein; PFAM: Domain of unknown function DUF11; TIGRFAM: conserved repeat domain. (931 aa)

Predicted Functional Partners:

AFY54585.1

0.773

AFY53781.1

0.760

AFY54580.1

0.756

AFY55128.1

0.743

AFY58141.1

0.740

AFY54578.1

0.735

AFY55648.1

0.710

AFY56018.1

0.690

AFY52768.1

0.671

AFY53008.1

0.652

Your Current Organism:

Rivularia sp. PCC7116

NCBI taxonomy Id: 373994
Other names: Calothrix sp. ATCC 29111, Calothrix sp. PCC 7116, R. sp. PCC 7116, Rivularia sp. LIP, Rivularia sp. PCC 7116

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFY52768.1	AFY53781.1	Riv7116_0159	Riv7116_1211	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	Hypothetical protein.	0.563
AFY52768.1	AFY54578.1	Riv7116_0159	Riv7116_2043	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	Putative N-acetylglucosaminyltransferase; PFAM: Core-2/I-Branching enzyme.	0.596
AFY52768.1	AFY54580.1	Riv7116_0159	Riv7116_2046	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	Putative N-acetylglucosaminyltransferase; PFAM: Core-2/I-Branching enzyme.	0.637
AFY52768.1	AFY54585.1	Riv7116_0159	Riv7116_2051	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	PFAM: O-Antigen ligase.	0.692
AFY52768.1	AFY55128.1	Riv7116_0159	Riv7116_2621	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.	0.445
AFY52768.1	AFY56018.1	Riv7116_0159	Riv7116_3566	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	PFAM: PBS lyase HEAT-like repeat.	0.481
AFY52768.1	AFY56042.1	Riv7116_0159	Riv7116_3591	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	Conserved repeat protein; PFAM: Domain of unknown function DUF11; TIGRFAM: conserved repeat domain.	0.671
AFY52768.1	AFY58141.1	Riv7116_0159	Riv7116_5775	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	Putative N-acetylglucosaminyltransferase; PFAM: Core-2/I-Branching enzyme.	0.606
AFY53008.1	AFY53781.1	Riv7116_0405	Riv7116_1211	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	Hypothetical protein.	0.606
AFY53008.1	AFY54580.1	Riv7116_0405	Riv7116_2046	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	Putative N-acetylglucosaminyltransferase; PFAM: Core-2/I-Branching enzyme.	0.453
AFY53008.1	AFY54585.1	Riv7116_0405	Riv7116_2051	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	PFAM: O-Antigen ligase.	0.703
AFY53008.1	AFY55128.1	Riv7116_0405	Riv7116_2621	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.	0.709
AFY53008.1	AFY55648.1	Riv7116_0405	Riv7116_3175	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	DGQHR domain-containing protein; TIGRFAM: DGQHR domain.	0.680
AFY53008.1	AFY56042.1	Riv7116_0405	Riv7116_3591	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	Conserved repeat protein; PFAM: Domain of unknown function DUF11; TIGRFAM: conserved repeat domain.	0.652
AFY53781.1	AFY52768.1	Riv7116_1211	Riv7116_0159	Hypothetical protein.	HEAT repeat-containing protein; PFAM: Adaptin N terminal region; HEAT repeat.	0.563
AFY53781.1	AFY53008.1	Riv7116_1211	Riv7116_0405	Hypothetical protein.	NB-ARC domain-containing protein; PFAM: NB-ARC domain.	0.606
AFY53781.1	AFY54578.1	Riv7116_1211	Riv7116_2043	Hypothetical protein.	Putative N-acetylglucosaminyltransferase; PFAM: Core-2/I-Branching enzyme.	0.583
AFY53781.1	AFY54580.1	Riv7116_1211	Riv7116_2046	Hypothetical protein.	Putative N-acetylglucosaminyltransferase; PFAM: Core-2/I-Branching enzyme.	0.682
AFY53781.1	AFY54585.1	Riv7116_1211	Riv7116_2051	Hypothetical protein.	PFAM: O-Antigen ligase.	0.773
AFY53781.1	AFY55128.1	Riv7116_1211	Riv7116_2621	Hypothetical protein.	PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.	0.707

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Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.814

expected number of edges:

14

PPI enrichment p-value:

7.44e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030527

Structural constituent of chromatin

3 of 3

2.44

1.79

0.00047

GO:0005198

Structural molecule activity

5 of 63

1.34

1.2

0.00067

GO:0003723

RNA binding

4 of 90

1.09

0.57

0.0402

GO:0003676

Nucleic acid binding

8 of 413

0.73

0.55

0.0032

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043232

Intracellular non-membrane-bounded organelle

4 of 87

1.1

0.63

0.0261

GO:0005840

Ribosome

3 of 55

1.18

0.63

0.0314

GO:0005622

Intracellular anatomical structure

10 of 1299

0.33

0.25

0.0345

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3126

Structural constituent of chromatin, and Periplasmic binding protein-like domain

3 of 6

2.14

1.41

0.0021

CL:1969

Tryptophan biosynthesis

2 of 7

1.9

0.69

0.0495

CL:88

Ribosomal protein, and Translation regulator activity

4 of 77

1.16

0.62

0.0313

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990104

DNA bending complex

2 of 2

2.44

1.19

0.0064

GOCC:0043232

Intracellular non-membrane-bounded organelle

6 of 112

1.17

1.1

0.00032

GOCC:0043590

Bacterial nucleoid

2 of 9

1.79

0.83

0.0247

GOCC:0005840

Ribosome

3 of 44

1.27

0.71

0.0234

GOCC:0043229

Intracellular organelle

7 of 376

0.71

0.51

0.0067

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0694

RNA-binding

5 of 68

1.31

1.18

0.00062

KW-0810

Translation regulation

2 of 5

2.04

0.84

0.0267

KW-0822

Tryptophan biosynthesis

2 of 6

1.96

0.83

0.0267

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00411

Bacterial (prokaryotic) histone like domain

3 of 3

2.44

2.21

6.85e-05

SM00316

Ribosomal protein S1-like RNA-binding domain

2 of 6

1.96

0.94

0.0161

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