STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY56656.1PFAM: GTP cyclohydrolase II; GTP cyclohydrolase N terminal. (417 aa)    
Predicted Functional Partners:
AFY56655.1
PFAM: Protein of unknown function (DUF1688).
     0.968
AFY54136.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
 0.945
AFY53724.1
PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit.
 
 
 0.894
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
  
 0.882
upp-2
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     0.613
AFY55592.1
Pyrimidine reductase, riboflavin biosynthesis; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain.
 
 
 0.525
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
  
 0.485
AFY52729.1
PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein.
  
  
 0.437
AFY56657.1
PFAM: Tetratricopeptide repeat.
       0.408
AFY52762.1
PFAM: CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 
 0.406
Your Current Organism:
Rivularia sp. PCC7116
NCBI taxonomy Id: 373994
Other names: Calothrix sp. ATCC 29111, Calothrix sp. PCC 7116, R. sp. PCC 7116, Rivularia sp. LIP, Rivularia sp. PCC 7116
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