STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kcr_0831PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: rba:RB8979 probable L-serine dehydratase, alpha chain. (486 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.968
Kcr_0521
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: tpe:Tpen_0611 threonine dehydratase.
  
 
 0.943
Kcr_1154
TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ape:APE_0683 phosphoserine phosphatase.
  
 
 0.928
trpB
Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
 0.901
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 
 0.893
Kcr_0008
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rci:LRC427 homoserine dehydrogenase.
 
 
 0.878
Kcr_1186
TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: pho:PH1146 aminomethyltransferase.
 
  
 0.615
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.581
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
       0.550
Kcr_0293
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: hbu:Hbut_0687 glutamine transport ATP-binding protein P.
  
 
 0.523
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeum cryptofilum OPF8, korarchaeote OPF1-KOR
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