node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Kcr_0150 | Kcr_1023 | Kcr_0150 | Kcr_1023 | KEGG: chy:CHY_1144 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | 0.838 |
Kcr_0150 | Kcr_1498 | Kcr_0150 | Kcr_1498 | KEGG: chy:CHY_1144 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pho:PH0923 phosphomannomutase; Belongs to the phosphohexose mutase family. | 0.456 |
Kcr_0150 | aroA | Kcr_0150 | Kcr_0249 | KEGG: chy:CHY_1144 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | DhnA-type fructose-1,6-bisphosphate aldolase-related enzyme; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 0.859 |
Kcr_0150 | eno | Kcr_0150 | Kcr_1606 | KEGG: chy:CHY_1144 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.989 |
Kcr_0150 | fbp | Kcr_0150 | Kcr_1467 | KEGG: chy:CHY_1144 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Fructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.830 |
Kcr_0150 | tpiA | Kcr_0150 | Kcr_1468 | KEGG: chy:CHY_1144 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.868 |
Kcr_0221 | Kcr_1023 | Kcr_0221 | Kcr_1023 | KEGG: pfu:PF0589 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | 0.918 |
Kcr_0221 | Kcr_1259 | Kcr_0221 | Kcr_1259 | KEGG: pfu:PF0589 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. | Glutamine--fructose-6-phosphate transaminase (isomerizing); PFAM: sugar isomerase (SIS); KEGG: mka:MK0127 glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domain. | 0.911 |
Kcr_0221 | Kcr_1498 | Kcr_0221 | Kcr_1498 | KEGG: pfu:PF0589 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. | PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pho:PH0923 phosphomannomutase; Belongs to the phosphohexose mutase family. | 0.978 |
Kcr_0221 | fbp | Kcr_0221 | Kcr_1467 | KEGG: pfu:PF0589 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. | Fructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.900 |
Kcr_0221 | glmS | Kcr_0221 | Kcr_1516 | KEGG: pfu:PF0589 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. | Glucosamine 6-phosphate synthetase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.911 |
Kcr_1023 | Kcr_0150 | Kcr_1023 | Kcr_0150 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | KEGG: chy:CHY_1144 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.838 |
Kcr_1023 | Kcr_0221 | Kcr_1023 | Kcr_0221 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | KEGG: pfu:PF0589 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. | 0.918 |
Kcr_1023 | Kcr_1259 | Kcr_1023 | Kcr_1259 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | Glutamine--fructose-6-phosphate transaminase (isomerizing); PFAM: sugar isomerase (SIS); KEGG: mka:MK0127 glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domain. | 0.902 |
Kcr_1023 | Kcr_1498 | Kcr_1023 | Kcr_1498 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pho:PH0923 phosphomannomutase; Belongs to the phosphohexose mutase family. | 0.920 |
Kcr_1023 | Kcr_1608 | Kcr_1023 | Kcr_1608 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | PFAM: sugar isomerase (SIS); KEGG: smr:Smar_0385 sugar isomerase (SIS). | 0.940 |
Kcr_1023 | aroA | Kcr_1023 | Kcr_0249 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | DhnA-type fructose-1,6-bisphosphate aldolase-related enzyme; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 0.839 |
Kcr_1023 | eno | Kcr_1023 | Kcr_1606 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.852 |
Kcr_1023 | fbp | Kcr_1023 | Kcr_1467 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | Fructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.909 |
Kcr_1023 | glmS | Kcr_1023 | Kcr_1516 | PFAM: glucose-6-phosphate isomerase; KEGG: afu:AF1494 putative glucose-6-phosphate isomerase. | Glucosamine 6-phosphate synthetase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.902 |