Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Kcr_1069Hydrolase of the metallo-beta-lactamase superfamily-like protein; KEGG: mth:MTH912 hypothetical protein. (476 aa)    
Predicted Functional Partners:
Kcr_0699
PFAM: beta-lactamase domain protein; KEGG: pth:PTH_0698 predicted exonuclease of the beta-lactamase fold.
  
  
 
0.926
Kcr_1071
SAM-dependent methyltransferase; PFAM: protein of unknown function Met10; KEGG: ape:APE_0141.1 hypothetical protein.
  
    0.816
Kcr_1070
Xaa-Pro aminopeptidase; PFAM: creatinase; peptidase M24; KEGG: pab:PAB1637 cobalt-dependent proline dipeptidase.
  
    0.755
Kcr_1079
PFAM: Polyprenyl synthetase; KEGG: tet:TTHERM_00268030 Polyprenyl synthetase family protein Pfam: polyprenyl_synt PROSITE: POLYPRENYL_SYNTHET_2; Belongs to the FPP/GGPP synthase family.
  
    0.588
Kcr_1269
PFAM: Polyprenyl synthetase; KEGG: nmu:Nmul_A1814 farnesyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
    0.588
Kcr_1068
Nicotinic acid phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; Nicotinate phosphoribosyltransferase and related; KEGG: tko:TK1676 nicotinate phosphoribosyltransferase.
       0.495
rpl37ae
Ribosomal L37ae protein; Binds to the 23S rRNA.
   
    0.455
Kcr_1522
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.429
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
  
 0.420
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
 
  
 0.417
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeum cryptofilum OPF8, korarchaeote OPF1-KOR
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