STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kcr_1221PFAM: protein of unknown function DUF75; KEGG: tpe:Tpen_0198 protein of unknown function DUF75. (251 aa)    
Predicted Functional Partners:
Kcr_1222
PFAM: band 7 protein; KEGG: pai:PAE0262 prohibitin homolog (HflK family).
       0.757
Kcr_1223
Predicted DNA-binding protein with PD1-like DNA-binding motif; PFAM: protein of unknown function DUF296; KEGG: pab:PAB0835 hypothetical protein.
       0.757
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.663
rpl18e
PFAM: ribosomal protein L15; KEGG: smr:Smar_0816 ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family.
  
     0.629
Kcr_1418
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: pfu:PF2055 hypothetical protein.
  
     0.626
Kcr_1594
PFAM: Protein of unknown function DUF655; KEGG: pab:PAB0252 putative nucleotide binding protein.
 
     0.622
cca
tRNA adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
     0.601
polC
DNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
  
     0.596
Kcr_0996
PFAM: protein of unknown function DUF120; KEGG: afu:AF2106 putative transcriptional regulator.
  
     0.595
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
  
     0.570
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeum cryptofilum OPF8, korarchaeote OPF1-KOR
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