STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carSCDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (158 aa)    
Predicted Functional Partners:
Kcr_1480
UbiA prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
    
 0.937
Kcr_0058
Dehydrogenase (flavoprotein); TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: tpe:Tpen_0114 FAD dependent oxidoreductase.
     
 0.906
Kcr_1359
TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase; KEGG: tpe:Tpen_0718 geranylgeranyl reductase.
     
 0.906
Kcr_1436
Rad51 domain protein; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
       0.799
Kcr_1439
PFAM: DEAD_2 domain protein; SMART: DEXDc2; helicase c2; KEGG: pho:PH0697 hypothetical protein.
       0.797
Kcr_1438
Hypothetical protein.
       0.773
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
   
 0.634
ftsZ-3
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
       0.598
Kcr_0350
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
    0.573
Kcr_0703
Ribonuclease HII/HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
    0.573
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeum cryptofilum OPF8, korarchaeote OPF1-KOR
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