STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (431 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
APG08575.1
Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
 0.947
APG08209.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.895
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
 
 0.872
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.859
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.855
atpA
F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
 
    
 0.842
APG07760.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
    
 0.839
glnA
Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.839
glnII
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.839
Your Current Organism:
Bradyrhizobium japonicum
NCBI taxonomy Id: 375
Other names: ATCC 10324, B. japonicum, Bradyrhizobium sp. BC-P14, Bradyrhizobium sp. SEMIA 511, Bradyrhizobium sp. SEMIA 6154, Bradyrhizobium sp. mas14, Bradyrhizobium sp. mas32, Bradyrhizobium sp. mas33, Bradyrhizobium sp. mas35, Bradyrhizobium sp. mas36, Bradyrhizobium sp. mas37, Bradyrhizobium sp. mas38, Bradyrhizobium sp. mas39, Bradyrhizobium sp. mas4, Bradyrhizobium sp. mas43, Bradyrhizobium sp. mas44, Bradyrhizobium sp. mas45, Bradyrhizobium sp. mas48, Bradyrhizobium sp. mas5, CCUG 27876, CIP 106093, DSM 30131, DSMZ 30131, HAMBI 2314, IFO 14783, JCM 20679, LMG 6138, LMG:6138, NBRC 14783, NRRL B-4507, NRRL L-241, Rhizobacterium japonicum, Rhizobium japonicum, USDA 6
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.