STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoHRNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (299 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.943
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.932
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.910
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.902
nusA
Transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination.
 
 
 0.899
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
 
  
 0.835
APG06850.1
CarD family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.822
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.798
dksA
RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
 
 
 0.792
yidC
Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
  
 0.786
Your Current Organism:
Bradyrhizobium japonicum
NCBI taxonomy Id: 375
Other names: ATCC 10324, B. japonicum, Bradyrhizobium sp. BC-P14, Bradyrhizobium sp. SEMIA 511, Bradyrhizobium sp. SEMIA 6154, Bradyrhizobium sp. mas14, Bradyrhizobium sp. mas32, Bradyrhizobium sp. mas33, Bradyrhizobium sp. mas35, Bradyrhizobium sp. mas36, Bradyrhizobium sp. mas37, Bradyrhizobium sp. mas38, Bradyrhizobium sp. mas39, Bradyrhizobium sp. mas4, Bradyrhizobium sp. mas43, Bradyrhizobium sp. mas44, Bradyrhizobium sp. mas45, Bradyrhizobium sp. mas48, Bradyrhizobium sp. mas5, CCUG 27876, CIP 106093, DSM 30131, DSMZ 30131, HAMBI 2314, IFO 14783, JCM 20679, LMG 6138, LMG:6138, NBRC 14783, NRRL B-4507, NRRL L-241, Rhizobacterium japonicum, Rhizobium japonicum, USDA 6
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