STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DVH24_021106ENTH domain-containing protein. (660 aa)    
Predicted Functional Partners:
DVH24_005779
AP-2 complex subunit alpha; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.
   
 0.587
DVH24_038983
AP-2 complex subunit alpha; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.
   
 0.587
DVH24_019717
Protein kinase domain-containing protein.
    
 0.581
DVH24_024352
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.553
DVH24_038449
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.553
DVH24_022934
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.553
DVH24_012613
ENTH domain-containing protein.
   
 0.480
DVH24_030694
Ubiquitin-like domain-containing protein.
    
  0.469
DVH24_039499
Ubiquitin-like domain-containing protein.
    
  0.469
DVH24_036275
Ubiquitin-like domain-containing protein.
    
  0.469
Your Current Organism:
Malus domestica
NCBI taxonomy Id: 3750
Other names: M. domestica, Malus communis, Malus communis Desf., Malus domestica Borkh., nom. cons. prop., Malus pumila auct., Malus pumila var. domestica, Malus pumila var. domestica (Borkh.) C.K.Schneid., Malus sylvestris var. domestica, Malus sylvestris var. domestica (Borkh.) Mansf., Malus x domestica, Pyrus malus, Pyrus malus L., apple, apple tree, cultivated apple
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