STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DVH24_026674Peptidylprolyl isomerase. (564 aa)    
Predicted Functional Partners:
DVH24_021259
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
    
 
 0.940
DVH24_014458
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
    
 
 0.940
DVH24_024139
S5A_REDUCTASE domain-containing protein.
    
 
 0.930
DVH24_033743
Uncharacterized protein.
   
 
 0.896
DVH24_040960
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.896
DVH24_037653
CS domain-containing protein.
   
 0.711
DVH24_037805
CS domain-containing protein.
   
 0.711
DVH24_008791
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.629
DVH24_000679
SH3 domain-containing protein.
  
 0.605
DVH24_016381
SH3 domain-containing protein.
  
 0.603
Your Current Organism:
Malus domestica
NCBI taxonomy Id: 3750
Other names: M. domestica, Malus communis, Malus communis Desf., Malus domestica Borkh., nom. cons. prop., Malus pumila auct., Malus pumila var. domestica, Malus pumila var. domestica (Borkh.) C.K.Schneid., Malus sylvestris var. domestica, Malus sylvestris var. domestica (Borkh.) Mansf., Malus x domestica, Pyrus malus, Pyrus malus L., apple, apple tree, cultivated apple
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