Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANK61557.1Glutathione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)    
Predicted Functional Partners:
ANK61613.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
  
 0.914
ANK62213.1
Glutathione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.913
ANK63483.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.772
ANK61558.1
Glycine/betaine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.677
ANK62154.1
Thiol reductase thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.676
ANK61764.1
Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.639
ANK61982.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.581
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.542
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.478
prs-2
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.478
Your Current Organism:
Lactobacillus backii
NCBI taxonomy Id: 375175
Other names: DSM 18080, JCM 18665, L. backii, LMG 23555, LMG:23555, Lactobacillus backi, Lactobacillus backii Tohno et al. 2013, strain L1062
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