STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (268 aa)    
Predicted Functional Partners:
thiE
Thiamine phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
ANK61840.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
ANK62202.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
ANK63130.1
ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
ANK61842.1
Hydroxymethylpyrimidine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.891
ANK62896.1
Energy coupling factor transporter S component ThiW; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.697
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.433
ANK63044.1
Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.415
Your Current Organism:
Lactobacillus backii
NCBI taxonomy Id: 375175
Other names: DSM 18080, JCM 18665, L. backii, LMG 23555, LMG:23555, Lactobacillus backi, Lactobacillus backii Tohno et al. 2013, strain L1062
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