Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANK61891.1Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (267 aa)    
Predicted Functional Partners:
srlA
PTS glucitol/sorbitol transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.993
ANK61894.1
PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.989
ANK61895.1
PTS sorbitol transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.989
ANK61892.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
   0.941
ANK63513.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.922
fbp
Class 3; catalyzes the formation of fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.917
ANK63412.1
PTS sorbitol transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.916
pfkA
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.913
ANK63224.1
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family.
   
 
 0.904
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.903
Your Current Organism:
Lactobacillus backii
NCBI taxonomy Id: 375175
Other names: DSM 18080, JCM 18665, L. backii, LMG 23555, LMG:23555, Lactobacillus backi, Lactobacillus backii Tohno et al. 2013, strain L1062
Server load: high (94%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.