| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANK62298.1 | ANK62299.1 | AYR53_05605 | AYR53_05610 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.565 |
| ANK62299.1 | ANK62298.1 | AYR53_05610 | AYR53_05605 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.565 |
| ANK62299.1 | ANK62300.1 | AYR53_05610 | AYR53_05615 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Antibiotic resistance protein VanZ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.733 |
| ANK62299.1 | ANK63470.1 | AYR53_05610 | AYR53_12270 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.523 |
| ANK62299.1 | glmU | AYR53_05610 | AYR53_05630 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.784 |
| ANK62299.1 | guaA | AYR53_05610 | AYR53_05840 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.698 |
| ANK62299.1 | prs-2 | AYR53_05610 | AYR53_05635 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.506 |
| ANK62299.1 | purA | AYR53_05610 | AYR53_03075 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.632 |
| ANK62299.1 | purF | AYR53_05610 | AYR53_02580 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.492 |
| ANK62299.1 | pyrH | AYR53_05610 | AYR53_08435 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.477 |
| ANK62299.1 | pyrR | AYR53_05610 | AYR53_09260 | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.497 |
| ANK62300.1 | ANK62299.1 | AYR53_05615 | AYR53_05610 | Antibiotic resistance protein VanZ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.733 |
| ANK63470.1 | ANK62299.1 | AYR53_12270 | AYR53_05610 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |
| ANK63470.1 | guaA | AYR53_12270 | AYR53_05840 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.907 |
| ANK63470.1 | prs-2 | AYR53_12270 | AYR53_05635 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.496 |
| ANK63470.1 | purA | AYR53_12270 | AYR53_03075 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.999 |
| ANK63470.1 | purF | AYR53_12270 | AYR53_02580 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.994 |
| glmU | ANK62299.1 | AYR53_05630 | AYR53_05610 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.784 |
| glmU | prs-2 | AYR53_05630 | AYR53_05635 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.952 |
| glmU | pyrH | AYR53_05630 | AYR53_08435 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.414 |
