STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
birABifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (323 aa)    
Predicted Functional Partners:
ANK63111.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 
 0.953
ANK62649.1
BioY family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.935
ANK62585.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.928
tadA
tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.913
ANK62876.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.881
fabH
Lactate oxidase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
   
 0.832
AYR53_06485
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.831
ANK63282.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.830
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.821
ANK62140.1
An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.815
Your Current Organism:
Lactobacillus backii
NCBI taxonomy Id: 375175
Other names: DSM 18080, JCM 18665, L. backii, LMG 23555, LMG:23555, Lactobacillus backi, Lactobacillus backii Tohno et al. 2013, strain L1062
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