| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANK61330.1 | ANK63338.1 | AYR53_00310 | AYR53_11490 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.542 |
| ANK61362.1 | ANK63338.1 | AYR53_00480 | AYR53_11490 | Competence protein ComA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.852 |
| ANK61362.1 | cinA | AYR53_00480 | AYR53_11485 | Competence protein ComA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | 0.410 |
| ANK61362.1 | folD | AYR53_00480 | AYR53_09980 | Competence protein ComA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.444 |
| ANK61362.1 | guaB | AYR53_00480 | AYR53_02345 | Competence protein ComA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.448 |
| ANK62243.1 | ANK62776.1 | AYR53_05315 | AYR53_08450 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | CDP-diglyceride synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.420 |
| ANK62243.1 | ANK63338.1 | AYR53_05315 | AYR53_11490 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.721 |
| ANK62243.1 | guaB | AYR53_05315 | AYR53_02345 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.571 |
| ANK62776.1 | ANK62243.1 | AYR53_08450 | AYR53_05315 | CDP-diglyceride synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.420 |
| ANK62776.1 | ANK63338.1 | AYR53_08450 | AYR53_11490 | CDP-diglyceride synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.952 |
| ANK63159.1 | ANK63338.1 | AYR53_10520 | AYR53_11490 | Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.589 |
| ANK63338.1 | ANK61330.1 | AYR53_11490 | AYR53_00310 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.542 |
| ANK63338.1 | ANK61362.1 | AYR53_11490 | AYR53_00480 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Competence protein ComA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | 0.852 |
| ANK63338.1 | ANK62243.1 | AYR53_11490 | AYR53_05315 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.721 |
| ANK63338.1 | ANK62776.1 | AYR53_11490 | AYR53_08450 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diglyceride synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.952 |
| ANK63338.1 | ANK63159.1 | AYR53_11490 | AYR53_10520 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.589 |
| ANK63338.1 | cinA | AYR53_11490 | AYR53_11485 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | 0.939 |
| ANK63338.1 | folD | AYR53_11490 | AYR53_09980 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.539 |
| ANK63338.1 | guaB | AYR53_11490 | AYR53_02345 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.534 |
| ANK63338.1 | mprF | AYR53_11490 | AYR53_12050 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.613 |