STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANK63402.1Phage antirepressor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)    
Predicted Functional Partners:
ANK63401.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.746
ANK63371.1
Terminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.687
ANK63403.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.670
ANK63369.1
Portal protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.666
ANK63373.1
HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.657
ANK63368.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.622
ANK63398.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
    0.601
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.575
ANK61832.1
Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
  
 0.571
ANK63404.1
Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.565
Your Current Organism:
Lactobacillus backii
NCBI taxonomy Id: 375175
Other names: DSM 18080, JCM 18665, L. backii, LMG 23555, LMG:23555, Lactobacillus backi, Lactobacillus backii Tohno et al. 2013, strain L1062
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.