STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (342 aa)    
Predicted Functional Partners:
ANK63430.1
Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.937
ANK63431.1
1,2-diacylglycerol 3-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.893
ANK62665.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.705
ANK63428.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.643
ANK62286.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.595
ANK63427.1
Glycerol phosphate lipoteichoic acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.590
ANK61344.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.573
ANK63124.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.511
ANK62245.1
Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.490
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.474
Your Current Organism:
Lactobacillus backii
NCBI taxonomy Id: 375175
Other names: DSM 18080, JCM 18665, L. backii, LMG 23555, LMG:23555, Lactobacillus backi, Lactobacillus backii Tohno et al. 2013, strain L1062
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