Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tolC1Outer membrane protein, tolC-like. (475 aa)    
Predicted Functional Partners:
acrA1
Membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.888
acrB1
Multidrug efflux pump, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.845
acrA5
Acriflavin resistance lipoprotein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.773
acrA3
Multidrug efflux system transmembrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.745
acrB3
Acriflavin resistance transmembrane protein.
 
   0.736
yegM
HlyD family secretion protein; Similar to yegM (Escherichia coli); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.730
mma_1565
Multidrug-efflux system protein.
 
   0.728
emrA
Multidrug resistance protein A, emrA.
 
 
 0.624
acrA4
Membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.618
mma_0023
Two-components system response regulator.
   
   0.589
Your Current Organism:
Janthinobacterium sp. Marseille
NCBI taxonomy Id: 375286
Other names: J. sp. Marseille, Minibacterium massiliensis
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