Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aro8Transcriptional regulator. (397 aa)    
Predicted Functional Partners:
mma_0721
2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
  0.916
aspB1
Aspartate aminotransferase.
   
 0.906
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.902
mma_0436
Serine--glyoxylate aminotransferase.
  
 
  0.901
glcD1
Glycolate oxidase (fad-linked subunit) oxidoreductase protein.
     
  0.900
glcE
Glycolate oxidase, subunit GlcE.
     
  0.900
glcF
Glycolate oxidase (iron-sulfur subunit).
     
  0.900
gcl
Tartronate-semialdehyde synthase; Belongs to the TPP enzyme family.
     
  0.900
lpdA
Dihydrolipoamide dehydrogenase.
     
  0.900
pdhD1
Dihydrolipoamide dehydrogenase.
     
  0.900
Your Current Organism:
Janthinobacterium sp. Marseille
NCBI taxonomy Id: 375286
Other names: J. sp. Marseille, Minibacterium massiliensis
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