ligA protein (Janthinobacterium sp. Marseille)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ligA

DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (692 aa)

Predicted Functional Partners:

def3

0.848

galU

0.842

zipA

0.842

leuS

0.798

polA

0.742

pheT

0.701

rep

0.684

uvrD

0.672

sun

0.625

mma_1029

0.625

Your Current Organism:

Janthinobacterium sp. Marseille

NCBI taxonomy Id: 375286
Other names: J. sp. Marseille, Minibacterium massiliensis

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
def3	galU	mma_2063	mma_2064	N-formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	UTP--glucose-1-phosphate uridylyltransferase.	0.842
def3	ligA	mma_2063	mma_2065	N-formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	0.848
def3	polA	mma_2063	mma_0323	N-formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.495
def3	zipA	mma_2063	mma_2066	N-formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Uncharacterized conserved protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.	0.841
galU	def3	mma_2064	mma_2063	UTP--glucose-1-phosphate uridylyltransferase.	N-formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.842
galU	ligA	mma_2064	mma_2065	UTP--glucose-1-phosphate uridylyltransferase.	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	0.842
galU	uvrD	mma_2064	mma_0319	UTP--glucose-1-phosphate uridylyltransferase.	DNA helicase II / ATP-dependent DNA helicase.	0.445
galU	zipA	mma_2064	mma_2066	UTP--glucose-1-phosphate uridylyltransferase.	Uncharacterized conserved protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.	0.841
leuS	ligA	mma_2896	mma_2065	leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	0.798
leuS	pheT	mma_2896	mma_1492	leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.965
leuS	polA	mma_2896	mma_0323	leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.537
ligA	def3	mma_2065	mma_2063	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	N-formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.848
ligA	galU	mma_2065	mma_2064	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	UTP--glucose-1-phosphate uridylyltransferase.	0.842
ligA	leuS	mma_2065	mma_2896	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.798
ligA	mma_1029	mma_2065	mma_1029	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	ATP-dependent DNA helicase.	0.625
ligA	pheT	mma_2065	mma_1492	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.701
ligA	polA	mma_2065	mma_0323	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.742
ligA	rep	mma_2065	mma_3592	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.	0.684
ligA	sun	mma_2065	mma_0158	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	tRNA and rRNA cytosine-C5-methylases; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.625
ligA	uvrD	mma_2065	mma_0319	DNA ligase (Polydeoxyribonucleotide synthase); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	DNA helicase II / ATP-dependent DNA helicase.	0.672

page 1 of 3

Server load: low (24%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Textmining

Co-occurrence

Databases

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About