| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bamB | hflC2 | mma_2124 | mma_2119 | Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | 0.695 |
| bamB | hflK | mma_2124 | mma_2120 | Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Membrane protease subunit HflK; HflC and HflK could encode or regulate a protease. | 0.646 |
| bamB | hflX | mma_2124 | mma_2121 | Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | HflX GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.595 |
| bamB | hfq | mma_2124 | mma_2122 | Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.719 |
| bamB | hisZ | mma_2124 | mma_2118 | Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.488 |
| bamB | mma_2125 | mma_2124 | mma_2125 | Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Uncharacterized conserved protein. | 0.968 |
| ftsH | hflC2 | mma_2237 | mma_2119 | Peptidase M41 (cell division protein); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | 0.915 |
| ftsH | hflK | mma_2237 | mma_2120 | Peptidase M41 (cell division protein); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Membrane protease subunit HflK; HflC and HflK could encode or regulate a protease. | 0.954 |
| ftsH | hflX | mma_2237 | mma_2121 | Peptidase M41 (cell division protein); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | HflX GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.633 |
| ftsH | hfq | mma_2237 | mma_2122 | Peptidase M41 (cell division protein); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.528 |
| ftsH | yidC | mma_2237 | mma_3694 | Peptidase M41 (cell division protein); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Preprotein translocase YidC subunit; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.451 |
| hflC2 | bamB | mma_2119 | mma_2124 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.695 |
| hflC2 | ftsH | mma_2119 | mma_2237 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | Peptidase M41 (cell division protein); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.915 |
| hflC2 | hflK | mma_2119 | mma_2120 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | Membrane protease subunit HflK; HflC and HflK could encode or regulate a protease. | 0.998 |
| hflC2 | hflX | mma_2119 | mma_2121 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | HflX GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.823 |
| hflC2 | hfq | mma_2119 | mma_2122 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.660 |
| hflC2 | hisZ | mma_2119 | mma_2118 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.584 |
| hflC2 | mma_2116 | mma_2119 | mma_2116 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | Nucleotide phosphoribosyltransferase. | 0.557 |
| hflC2 | mma_2125 | mma_2119 | mma_2125 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | Uncharacterized conserved protein. | 0.513 |
| hflC2 | purA1 | mma_2119 | mma_2117 | Inner membrane-anchored protein; HflC and HflK could regulate a protease. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.597 |