| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceB | acs | mma_1942 | mma_0882 | Malate synthase; Belongs to the malate synthase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.937 |
| aceB | gltA | mma_1942 | mma_1511 | Malate synthase; Belongs to the malate synthase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.947 |
| aceB | mdh | mma_1942 | mma_1504 | Malate synthase; Belongs to the malate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.941 |
| aceB | prpB | mma_1942 | mma_3487 | Malate synthase; Belongs to the malate synthase family. | Carboxyvinyl-carboxyphosphonate phosphorylmutase. | 0.809 |
| aceB | prpC | mma_1942 | mma_3488 | Malate synthase; Belongs to the malate synthase family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.947 |
| aceB | prpE | mma_1942 | mma_3490 | Malate synthase; Belongs to the malate synthase family. | propionyl-CoA synthetase. | 0.487 |
| acnA | gltA | mma_1501 | mma_1511 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Citrate synthase; Belongs to the citrate synthase family. | 0.996 |
| acnA | mdh | mma_1501 | mma_1504 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.955 |
| acnA | prpB | mma_1501 | mma_3487 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Carboxyvinyl-carboxyphosphonate phosphorylmutase. | 0.698 |
| acnA | prpC | mma_1501 | mma_3488 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.996 |
| acnA | prpD | mma_1501 | mma_3489 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 2-methylcitrate dehydratase. | 0.935 |
| acs | aceB | mma_0882 | mma_1942 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Malate synthase; Belongs to the malate synthase family. | 0.937 |
| acs | gltA | mma_0882 | mma_1511 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase; Belongs to the citrate synthase family. | 0.935 |
| acs | prpB | mma_0882 | mma_3487 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Carboxyvinyl-carboxyphosphonate phosphorylmutase. | 0.476 |
| acs | prpC | mma_0882 | mma_3488 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.935 |
| acs | prpE | mma_0882 | mma_3490 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | propionyl-CoA synthetase. | 0.911 |
| gltA | aceB | mma_1511 | mma_1942 | Citrate synthase; Belongs to the citrate synthase family. | Malate synthase; Belongs to the malate synthase family. | 0.947 |
| gltA | acnA | mma_1511 | mma_1501 | Citrate synthase; Belongs to the citrate synthase family. | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.996 |
| gltA | acs | mma_1511 | mma_0882 | Citrate synthase; Belongs to the citrate synthase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.935 |
| gltA | mdh | mma_1511 | mma_1504 | Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.995 |