Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
idhIsocitrate dehydrogenase (NAD+). (349 aa)    
Predicted Functional Partners:
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.967
sucA
2-oxoglutarate dehydrogenase E1 component.
   
 0.936
icd
Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
     
 0.901
gltB
Glutamate synthase (NADPH) large chain.
  
 
 0.895
gabD
Succinate-semialdehyde dehydrogenase (NADP+).
   
 0.858
leuC2
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.833
argH
Argininosuccinate lyase.
  
 
 0.827
gdhA1
Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.822
gdhA2
Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.822
aspB1
Aspartate aminotransferase.
   
 0.813
Your Current Organism:
Janthinobacterium sp. Marseille
NCBI taxonomy Id: 375286
Other names: J. sp. Marseille, Minibacterium massiliensis
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