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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (360 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.989
hemF
Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
 0.972
hemN2
Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
 
 0.961
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.941
cobA
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
    
 0.917
cysG
uroporphyrin-III C-methyltransferase.
    
 0.917
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.909
hemX
uroporphyrin-III C-methyltransferase.
     
 0.904
hemB
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.851
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
  
 0.746
Your Current Organism:
Janthinobacterium sp. Marseille
NCBI taxonomy Id: 375286
Other names: J. sp. Marseille, Minibacterium massiliensis
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