STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icd-2Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)    
Predicted Functional Partners:
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.990
sucA
Alpha-ketoglutarate dehydrogenase.
   
 
 0.980
gltB
Glutamate synthase, large subunit.
    
 0.939
icd
Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family.
    
 0.929
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.921
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.917
gill
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.912
gdhA
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.912
tyrB
Aromatic amino acid aminotransferase.
   
 0.903
fhs
Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
 
 
  
 0.891
Your Current Organism:
Roseobacter denitrificans
NCBI taxonomy Id: 375451
Other names: Erythrobacter sp. OCh114, R. denitrificans OCh 114, Roseobacter denitrificans ATCC 33942, Roseobacter denitrificans DSM 7001, Roseobacter denitrificans OCh 114, Roseobacter denitrificans str. OCh 114, Roseobacter denitrificans strain OCh 114, Roseobacter sp. OCh114
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