node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RD1_2751 | acsA | RD1_2751 | RD1_1117 | 3-hydroxyisobutyrate dehydrogenase, putative. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.807 |
RD1_2751 | acsA-2 | RD1_2751 | RD1_2332 | 3-hydroxyisobutyrate dehydrogenase, putative. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.807 |
RD1_2751 | ald | RD1_2751 | RD1_0633 | 3-hydroxyisobutyrate dehydrogenase, putative. | Aldehyde dehydrogenase family protein, putative. | 0.912 |
RD1_2751 | ald-2 | RD1_2751 | RD1_0660 | 3-hydroxyisobutyrate dehydrogenase, putative. | Aldehyde dehydrogenase family protein, putative; Belongs to the aldehyde dehydrogenase family. | 0.912 |
RD1_2751 | fadJ | RD1_2751 | RD1_3973 | 3-hydroxyisobutyrate dehydrogenase, putative. | Fatty acid oxidation complex alpha subunit, putative. | 0.919 |
RD1_2751 | gabT | RD1_2751 | RD1_0839 | 3-hydroxyisobutyrate dehydrogenase, putative. | 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.900 |
RD1_2751 | garR-2 | RD1_2751 | RD1_2540 | 3-hydroxyisobutyrate dehydrogenase, putative. | 2-hydroxy-3-oxopropionate reductase, putative. | 0.927 |
RD1_2751 | mmsA | RD1_2751 | RD1_2990 | 3-hydroxyisobutyrate dehydrogenase, putative. | Methylmalonate-semialdehyde dehydrogenase. | 0.935 |
RD1_2751 | pccA | RD1_2751 | RD1_2032 | 3-hydroxyisobutyrate dehydrogenase, putative. | propionyl-CoA carboxylase, alpha subunit. | 0.821 |
RD1_2751 | prpE | RD1_2751 | RD1_3986 | 3-hydroxyisobutyrate dehydrogenase, putative. | propionate--CoA ligase. | 0.807 |
acsA | RD1_2751 | RD1_1117 | RD1_2751 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-hydroxyisobutyrate dehydrogenase, putative. | 0.807 |
acsA | acsA-2 | RD1_1117 | RD1_2332 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.900 |
acsA | ald | RD1_1117 | RD1_0633 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase family protein, putative. | 0.933 |
acsA | ald-2 | RD1_1117 | RD1_0660 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase family protein, putative; Belongs to the aldehyde dehydrogenase family. | 0.933 |
acsA | fadJ | RD1_1117 | RD1_3973 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Fatty acid oxidation complex alpha subunit, putative. | 0.925 |
acsA | gabT | RD1_1117 | RD1_0839 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.822 |
acsA | garR-2 | RD1_1117 | RD1_2540 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 2-hydroxy-3-oxopropionate reductase, putative. | 0.824 |
acsA | mmsA | RD1_1117 | RD1_2990 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Methylmalonate-semialdehyde dehydrogenase. | 0.933 |
acsA | pccA | RD1_1117 | RD1_2032 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | propionyl-CoA carboxylase, alpha subunit. | 0.917 |
acsA | prpE | RD1_1117 | RD1_3986 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | propionate--CoA ligase. | 0.912 |