node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RD1_2531 | thiD | RD1_2531 | RD1_0746 | Conserved hypothetical protein. | Phosphomethylpyrimidine kinase. | 0.414 |
RD1_2531 | thiD-2 | RD1_2531 | RD1_3612 | Conserved hypothetical protein. | Phosphomethylpyrimidine kinase. | 0.414 |
RD1_2531 | thiDE | RD1_2531 | RD1_3611 | Conserved hypothetical protein. | Bifunctional ThiED protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.721 |
RD1_2531 | thiE | RD1_2531 | RD1_0750 | Conserved hypothetical protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.721 |
RD1_2531 | thiE-2 | RD1_2531 | RD1_2730 | Conserved hypothetical protein. | Thiamine-phosphate pyrophosphorylase, putative. | 0.721 |
RD1_2531 | thiM | RD1_2531 | RD1_3610 | Conserved hypothetical protein. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.500 |
RD1_3595 | thiD | RD1_3595 | RD1_0746 | Two-component hybrid sensor and regulator, putative. | Phosphomethylpyrimidine kinase. | 0.519 |
RD1_3595 | thiD-2 | RD1_3595 | RD1_3612 | Two-component hybrid sensor and regulator, putative. | Phosphomethylpyrimidine kinase. | 0.519 |
RD1_3595 | thiDE | RD1_3595 | RD1_3611 | Two-component hybrid sensor and regulator, putative. | Bifunctional ThiED protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.509 |
RD1_3595 | thiE | RD1_3595 | RD1_0750 | Two-component hybrid sensor and regulator, putative. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.509 |
RD1_3595 | thiE-2 | RD1_3595 | RD1_2730 | Two-component hybrid sensor and regulator, putative. | Thiamine-phosphate pyrophosphorylase, putative. | 0.509 |
RD1_3595 | thiM | RD1_3595 | RD1_3610 | Two-component hybrid sensor and regulator, putative. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.508 |
tenA | tenA-2 | RD1_0753 | RD1_0755 | Transcriptional activator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Transcriptional regulator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | 0.994 |
tenA | tenA-3 | RD1_0753 | RD1_3613 | Transcriptional activator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Transcriptional regulator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.902 |
tenA | thiD | RD1_0753 | RD1_0746 | Transcriptional activator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Phosphomethylpyrimidine kinase. | 0.999 |
tenA | thiD-2 | RD1_0753 | RD1_3612 | Transcriptional activator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Phosphomethylpyrimidine kinase. | 0.996 |
tenA | thiDE | RD1_0753 | RD1_3611 | Transcriptional activator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Bifunctional ThiED protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.609 |
tenA | thiE | RD1_0753 | RD1_0750 | Transcriptional activator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.883 |
tenA | thiM | RD1_0753 | RD1_3610 | Transcriptional activator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.946 |
tenA-2 | tenA | RD1_0755 | RD1_0753 | Transcriptional regulator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Transcriptional activator, putative; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.994 |