Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLCN4Chloride voltage-gated channel 4. (623 aa)    
Predicted Functional Partners:
CLCN3
Chloride voltage-gated channel 3.
   
  0.988
TMEM9
Transmembrane protein 9.
    
 
 0.942
ENSCAPP00000005429
annotation not available
    
 
 0.902
LATS1
Large tumor suppressor kinase 1.
    
 0.836
PTPN14
Protein tyrosine phosphatase non-receptor type 14.
    
 0.764
LATS2
Large tumor suppressor kinase 2.
    
 0.749
NF2
Neurofibromin 2.
    
 0.739
FRMD6
FERM domain containing 6.
     
 0.724
GPR162
G protein-coupled receptor 162.
    
 
 0.695
ENSCAPP00000004616
annotation not available
    
 0.682
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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