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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WNT8AWnt family member 8A. (348 aa)    
Predicted Functional Partners:
WLS
Wnt ligand secretion mediator.
    
 0.947
NOTUM
Notum, palmitoleoyl-protein carboxylesterase.
    
 0.942
GPC3
Glypican 3.
    
 0.941
LRP6
LDL receptor related protein 6.
    
 0.926
FZD9
Frizzled class receptor 9.
    
 0.915
ENSCAPP00000011186
annotation not available
    
 0.915
CER1
Cerberus 1, DAN family BMP antagonist.
   
 
  0.910
PORCN
Porcupine O-acyltransferase.
    
 0.910
FZD3
Frizzled class receptor 3.
    
 0.906
FZD6
Frizzled class receptor 6.
    
 0.903
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.