STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WT1WT1 transcription factor. (298 aa)    
Predicted Functional Partners:
TP53
Tumor protein p53.
    
 0.773
NR5A1
Nuclear receptor subfamily 5 group A member 1.
    
 0.768
WTAP
WT1 associated protein.
    
 
 0.735
ENSCAPP00000006136
annotation not available
    
 0.728
SOX8
SRY-box transcription factor 8.
    
 0.674
SOX10
SRY-box transcription factor 10.
    
 0.646
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
 
 0.640
LMX1B
LIM homeobox transcription factor 1 beta.
    
 
 0.636
NR5A2
Nuclear receptor subfamily 5 group A member 2.
    
 0.628
MYBL2
MYB proto-oncogene like 2.
   
 
 0.626
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.