STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK3Polo like kinase 3. (476 aa)    
Predicted Functional Partners:
RANBP2
RAN binding protein 2.
   
 0.984
NEK9
NIMA related kinase 9.
   
0.984
ITSN2
Intersectin 2.
    
 0.981
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.981
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.979
CCNB2
Cyclin B2.
   
 0.977
CDC20
Cell division cycle 20.
   
 0.962
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.957
WDR41
WD repeat domain 41.
   
 0.956
ENSCAPP00000000974
annotation not available
   
0.946
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.