Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TATTyrosine aminotransferase. (491 aa)    
Predicted Functional Partners:
HPD
4-hydroxyphenylpyruvate dioxygenase.
   
 
 0.987
PAH
Phenylalanine hydroxylase.
   
 
 0.975
GOT2
Glutamic-oxaloacetic transaminase 2.
  
 0.965
GOT1
Glutamic-oxaloacetic transaminase 1.
  
 0.963
UBE3A
Ubiquitin protein ligase E3A.
    
   0.959
TYR
Tyrosinase.
     
 0.946
GOT1L1
Glutamic-oxaloacetic transaminase 1 like 1.
  
 0.944
ENSCAPP00000008622
annotation not available
   
 
  0.938
MAT1A
Methionine adenosyltransferase 1A.
  
 0.937
TH
Tyrosine hydroxylase.
   
 
 0.937
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]