STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE1Prickle planar cell polarity protein 1. (830 aa)    
Predicted Functional Partners:
VANGL2
VANGL planar cell polarity protein 2.
    
 0.979
VANGL1
VANGL planar cell polarity protein 1.
    
 0.978
DVL2
Dishevelled segment polarity protein 2.
    
 0.963
DVL1
Dishevelled segment polarity protein 1.
    
 0.952
DVL3
Dishevelled segment polarity protein 3.
    
 0.913
PRICKLE2
Prickle planar cell polarity protein 2.
    
 
0.837
FZD3
Frizzled class receptor 3.
    
 0.762
FZD6
Frizzled class receptor 6.
  
 
 0.737
ANKRD6
Ankyrin repeat domain 6.
    
 0.675
ENSCAPP00000017093
annotation not available
   
 0.663
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.