Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBX21T-box transcription factor 21. (432 aa)    
Predicted Functional Partners:
GATA3
GATA binding protein 3.
    
 0.995
IFNG
Interferon gamma.
   
 0.973
ENSCAPP00000000033
annotation not available
   
 0.912
RUNX3
RUNX family transcription factor 3.
   
 0.912
RUNX2
RUNX family transcription factor 2.
   
 0.886
STAT1
Signal transducer and activator of transcription 1.
    
 0.879
STAT4
Signal transducer and activator of transcription 4.
   
 0.844
STAT3
Signal transducer and activator of transcription 3.
    
 0.772
TNF
Tumor necrosis factor.
     
 0.771
IL17A
Interleukin 17A.
      
 0.757
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.