Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MARCHF1Membrane associated ring-CH-type finger 1. (289 aa)    
Predicted Functional Partners:
INSR
Insulin receptor.
    
 
 0.791
UBE2G2
Ubiquitin conjugating enzyme E2 G2.
    
 0.738
UBE2H
Ubiquitin conjugating enzyme E2 H.
   
 
 0.722
CNOT2
CCR4-NOT transcription complex subunit 2.
    
 0.688
VCP
Valosin containing protein.
    
 0.684
UFD1
Ubiquitin recognition factor in ER associated degradation 1.
    
 0.608
DOP1B
DOP1 leucine zipper like protein B.
      
 0.590
CD83
CD83 molecule.
      
 0.569
FAF1
Fas associated factor 1.
    
 0.551
FAF2
Fas associated factor family member 2.
    
 0.551
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.