Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MLLT10MLLT10 histone lysine methyltransferase DOT1L cofactor. (955 aa)    
Predicted Functional Partners:
DOT1L
DOT1 like histone lysine methyltransferase.
    
 
 0.979
MLLT1
MLLT1 super elongation complex subunit.
    
 
 0.971
MLLT6
MLLT6, PHD finger containing.
    
 
 0.963
ENSCAPP00000000712
annotation not available
    
 
 0.943
CARS1
cysteinyl-tRNA synthetase 1.
    
   0.829
CTNNB1
Catenin beta 1.
    
 
 0.825
ENSCAPP00000010353
annotation not available
    
   0.817
ENSCAPP00000009603
annotation not available
    
   0.810
EEF1G
Eukaryotic translation elongation factor 1 gamma.
    
   0.800
VARS1
valyl-tRNA synthetase 1.
    
   0.800
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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